SP-0350 Introduction to microbeam radiation therapy: radiosurgical grid therapy at the microscopic scale
نویسندگان
چکیده
منابع مشابه
Microbeam radiation therapy.
It is proposed to carry out radiotherapy and radiosurgery for brain lesions by crossfiring an array of parallel, closely spaced microbeams of synchrotron-generated x rays several times through an isocentric target, each microbeam in the array having an approximately 25-microns-wide adjustable-height rectangular cross section. The following inferences from the known tissue sparing of 22-MeV deut...
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Radiotherapeutic doses for malignant gliomas are generally palliative because greater, supposedly curative doses would impart clinically unacceptable damage to nearby vital CNS tissues. To improve radiation treatment for human gliomas, we evaluated microbeam radiation therapy, which utilizes an array of parallel, microscopically thin (<100 microm) planar beams (microbeams) of synchrotron-genera...
متن کاملMOSFET dosimetry for microbeam radiation therapy at the European Synchrotron Radiation Facility.
Preclinical experiments are carried out with approximately 20-30 microm wide, approximately 10 mm high parallel microbeams of hard, broad-"white"-spectrum x rays (approximately 50-600 keV) to investigate microbeam radiation therapy (MRT) of brain tumors in infants for whom other kinds of radiotherapy are inadequate and/or unsafe. Novel physical microdosimetry (implemented with MOSFET chips in t...
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J.A. Laissue , H. Blattmann 1 , M.A. Grotzer 2 , B. Kaser-Hotz , D.N. Slatkin , H.P. Wagner 5 1 Institut für Pathologie, Universität Bern, CH-3010 Bern, Switzerland 2 Universitäts-Kinderkliniken, CH-8032 Zürich, Switzerland 3 Vetsuisse Fakultät, Universität Zürich, CH-8057 Zürich, Switzerland 4 Brookhaven National Laboratory, Upton, New York 11973-5000, USA 5 Universitäts-Kinderkliniken des Ins...
متن کاملDose GRID increase the unwanted photoneutron dose to the patients in GRID therapy?
Introduction: GRID therapy is a treatment modality in which a high dose of radiation in a single fraction is given to the tumor. This technique previously was used to treat bulky tumors with orthovoltage beams. Recently, studies have been conducted to suggest that GRID therapy with megavoltage photons can be useful in palliative treatments. On the other hand, there has always ...
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ژورنال
عنوان ژورنال: Radiotherapy and Oncology
سال: 2019
ISSN: 0167-8140
DOI: 10.1016/s0167-8140(19)30770-4